Shinji Sakuma Selected Research

Thomsen-Friedenreich antigen

3/2019	Tumor recognition of peanut agglutinin-immobilized fluorescent nanospheres in biopsied human tissues.
11/2018	SPECIFIC MOLECULAR RECOGNITION AS A STRATEGY TO DELINEATE TUMOR MARGIN USING TOPICALLY APPLIED FLUORESCENCE EMBEDDED NANOPARTICLES.
1/2017	Evaluation of a novel fluorescent nanobeacon for targeted imaging of Thomsen-Friedenreich associated colorectal cancer.
3/2015	Fluorescence-based endoscopic imaging of Thomsen-Friedenreich antigen to improve early detection of colorectal cancer.
5/2013	Multifunctional nanobeacon for imaging Thomsen-Friedenreich antigen-associated colorectal cancer.
12/2011	Lectin-immobilized fluorescent nanospheres for targeting to colorectal cancer from a physicochemical perspective.
11/2011	Essence of affinity and specificity of peanut agglutinin-immobilized fluorescent nanospheres with surface poly(N-vinylacetamide) chains for colorectal cancer.
3/2010	Detection of early colorectal cancer imaged with peanut agglutinin-immobilized fluorescent nanospheres having surface poly(N-vinylacetamide) chains.
2/2009	In vitro/in vivo biorecognition of lectin-immobilized fluorescent nanospheres for human colorectal cancer cells.
10/2008	Poly(N-vinylacetamide) chains enhance lectin-induced biorecognition through the reduction of nonspecific interactions with nontargets.

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Shinji Sakuma Research Topics

Disease

12	Neoplasms (Cancer) 01/2021 - 02/2009
10	Colorectal Neoplasms (Colorectal Cancer) 01/2017 - 10/2008
4	Infections 02/2022 - 01/2018
4	Virus Diseases (Viral Diseases) 12/2019 - 01/2016
2	Human Influenza (Influenza) 12/2019 - 01/2019
2	Carcinoma (Carcinomatosis) 03/2015 - 01/2002
1	Pancreatic Neoplasms (Pancreatic Cancer) 11/2018
1	Polyps 01/2017
1	Colonic Neoplasms (Colon Cancer) 07/2015
1	Neoplasm Metastasis (Metastasis) 03/2015

Drug/Important Bio-Agent (IBA)

10	Thomsen-Friedenreich antigenIBA 03/2019 - 10/2008
8	Peanut AgglutininIBA 03/2019 - 10/2008
7	SugarsIBA 03/2019 - 10/2008
7	poly(N-vinylacetamide)IBA 03/2019 - 03/2010
6	AntigensIBA 11/2018 - 03/2011
4	Immunoglobulin A (IgA)IBA 12/2019 - 01/2016
4	Polystyrenes (Polystyrene)IBA 03/2019 - 12/2011
4	LectinsIBA 03/2015 - 10/2008
3	octaarginineIBA 12/2019 - 01/2018
3	coumarin 6IBA 03/2015 - 03/2011
2	Immunoglobulin G (IgG)IBA 12/2019 - 01/2019
2	Viral AntigensIBA 12/2019 - 01/2019
2	coumarinIBA 03/2019 - 07/2015
2	Biomarkers (Surrogate Marker)IBA 01/2017 - 05/2013
2	CarbohydratesIBA 03/2015 - 02/2009
2	polymethacrylic acid (PMAA)IBA 11/2011 - 10/2008
2	Phenobarbital (Luminal)FDA Link 03/2010 - 02/2009
1	PolymersIBA 02/2022
1	DNA (Deoxyribonucleic Acid)IBA 01/2021
1	GuanineIBA 01/2021
1	Antineoplastic Agents (Antineoplastics)IBA 01/2021
1	OligonucleotidesIBA 01/2021
1	NucleolinIBA 01/2021
1	Proteins (Proteins, Gene)FDA Link 01/2021
1	Nucleotide AptamersIBA 01/2021
1	Hyaluronic Acid (Hyaluronan)IBA 12/2019
1	glycyl-glycyl-glycyl-glycineIBA 12/2019
1	Polysaccharides (Glycans)IBA 12/2019
1	acrylic acid (acrylate)IBA 01/2018
1	MucinsIBA 03/2015
1	Wheat Germ AgglutininsIBA 11/2011
1	methacrylic acidIBA 11/2011
1	Pharmaceutical PreparationsIBA 03/2011
1	Immunoglobulin Fab FragmentsIBA 01/2002
1	hydroxypropyl methacrylateIBA 01/2002

Therapy/Procedure

10	Nanospheres 03/2019 - 10/2008
1	Drug Therapy (Chemotherapy) 03/2015
1	Endoscopes 12/2011